Matches
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| Jornada | Fecha | Home team | Home team | |||
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| Jornada 1 | 05/07/2025 20:00:00 |  Cerro Porteño |
- |  General Caballero JLM |
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| Jornada 1 | 05/07/2025 20:00:00 |  Libertad |
- |  Sp. Luqueño |
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| Jornada 1 | 05/07/2025 20:00:00 |  Guaraní |
- |  2 de Mayo |
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| Jornada 1 | 05/07/2025 20:00:00 |  Olimpia |
- |  Nacional Asunción |
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| Jornada 1 | 05/07/2025 20:00:00 |  Recoleta |
- |  Sportivo Trinidense |
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| Jornada 1 | 05/07/2025 20:00:00 |  S. Ameliano |
- |  Atl. Tembetary |
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